Although he was tired, but he continued to work。
Although he is a great scientist, but he remains modest and works as an ordinary teacher in University。
If you don't want to run the risk of failure, you can try。
thought he tired he kept on working
even thought, he is a great scientist, he always keep a modest attitude and works as a common teacher in university
if you fear no risk you can try
Although he was tired, he still insisted on working.