Dear Mr. Smith
This is Danny from ABC company .
I'm writing to inform you that our manager is not avaiable this aftrenoon ,as his child is ill in hospital now.
Great sorry for the trouble to you !
I'd like to confirm that if you are available this friday afternoon in the NO.2 conference room of DFE hotel .
Your prompt reply will be highly appreciated .
Thank you !
Best regards !
Danny
ABC company